From: email@example.com(Steven B. Harris)
Subject: Re: Syndrome X- Need Information
Date: 23 Feb 1999 04:16:09 GMT
In <firstname.lastname@example.org> email@example.com writes:
>My nephrologist has mentioned that I probably have a set of symptoms
>called Syndrome X which includes the symptoms of high BP, blood sugar
>problems, high cholesterol, high triglycerides, weight gain in middle
>body, and heart problems. I have these without outright heart
>problems but my kidneys are showing signs of degeneration
>I have read that these symptoms are related to insulin resistence and
>I'd like to know more about all of this. Anybody have suggestions of
>sources of information. I've searched the web for syndrome x but
>didn't find much. I'd love to get a book that handles all of this.
>Thanks. Please email me if possible.
>Paul Getty, DDS
>Morehead City NC
You don't search the web, you search Medline.
Just type in syndrome X.
Good luck. I suggest dietary restriction (a low fat diet), aerobic
exercise, and Rezulin (which you need liver tests to take, once a month
for 8 months-- don't miss one). Rezulin in an insulin sensitizing
antioxidant which has deep effects on genetic expression. It does so
many things (including lowering blood pressure and glucose and even
cholesterol) that I suspect it's somehow interfering with part of the
core complex of whatever the defect is in syndrome X (which we don't
understand, but do know is tied to getting too many calories). Rezulin
will not help you lose weight, alas-- you need to do that yourself.
Other than saturated fat, nutrients which seem to be related to the
complex of problems and effects of syndrome X are magnesium (a gram a
day), vitamin C (several grams a day), and biotin (5 mg twice a day).
They favorably affect blood pressure (magnesium) and insulin
sensitivity (vit C and biotin). These supplements, plus a
multivitamin, are relatively cheap compared with pharmaceuticals. The
science behind them is sketchy but suggestive, and they're less
expensive and dangerous than Rezulin. But also less effective. So
it's a tradeoff. Exercise and weight loss are the only sure
Steve Harris, M.D.